Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information

What is the source and function of the Lacto Exosome in Zero Exosome Shot?

The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps b

Is it normal for my face to tingle after application?

It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

Do I simply wash it off or do I maintain my regular skincare routine afterwards?

This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.

Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?

The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.

Are there any ingredients that should not be used together with it?

There are no restricted ingredients with this product, but those with sensitive skin should be cautious. Perform a patch test and adjust usage based on your skin's reaction

I want to focus on managing my pores. Are there any synergistic products that work well together?

Using Exosome Shot with One-day Serum and Cream improves pore volume by 88% and area by 85% compared to using the shot alone. Apply Exosome Shot, then Serum, and Cream for best results. Results from tests; individual outcomes may vary.

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Reviews

M**D

Do your skin a favour! Try this!! Amazing!

Fantastic product!! It does feel strange to start with but it truly works on making your skin so hydrated and helps other products absorb into your skin so much better !! My skin clarity has never been as good and at 61 years young that’s what I want !!

23.01.2026

L**A

Amazing product

I loved my skin is soft and very glow

6.02.2026

C**L

Glowing skin, no irritation

I went straight to this without the lower strength. Easy to use, no irritation or dryness. Lovely glow in the morning. No scent that I smelled. Absorbed in well and I could layer oil, wrapping mask, cream, you name it on top with no issue. A little goes a long way so good value for money for this effective product. I found 0 pain or stinging at all! My only gripe is I want to use every night lol.

15.02.2026

K**E

Good product

The tingles are no joke but after a few applications (every 3 days) you do get used to it. My skin feels so soft but haven’t seen any pore reduction just yet

5.12.2025

D**A

Medicube zero shot 2000

Love medicube but think this may well be my favourite so far . The feeling is quite mild not bad at all I bought the milder version to try first . Been using it a few days now and love it I honestly believe it definitely helps your other skin care to go deep into your skin. Have seen even more improvement. In my skin since using this shot . It doesn’t hurt at all just gentle press into your skin and see an improvement then apply all your other medicube skin products love it thank you

14.02.2026

R**U

I recommend it

Lives skin even and soft

14.02.2026

B**3

Love it!

Great stuff! It really does help! I use this together with the PDRN serum, and it did wonders in less than a week. Prescriptions couldn't do that! I have combination skin, and it makes my oily areas balanced. If you have dry or very dry skin, expect it to be a bit drying. You must moisturize after or use it every other day. Definitely go with the 2000 first. Also ensure you buy from the official medicube seller!

22.01.2026

T**S

PLEASE READ MY REVIEW THANK YOU

WOW! This is an amazing little blue bottle, as it’s my first time I’ve been using it twice a week at night. It’s like just like micro-needling (lots of moisturiser after you’ve used it) my skin looks amazing the next day & for days after, really happy & will repurchase.

15.02.2026

ASIN	B0D16L5F2M
Benefits	Visibly refines the pores, improves the skin structure and ensures an even complexion, supports the regeneration of the skin and strengthens the skin barrier, increases radiance and provides a healthy glow, ideal for daily use for all skin types
Best Sellers Rank	386 in Beauty ( See Top 100 in Beauty ) 13 in Face Serums
Brand	medicube
Brand Name	medicube
Country Of Origin	Korea, Republic of
Customer Reviews	4.5 out of 5 stars 7,572 Reviews
Item Form	Drop
Item Volume	0.4 Kilograms
Item Weight	30 Milligrams
Item form	Drop
Item volume	0.4 Kilograms
Item weight	30 Milligrams
Manufacturer	Medicube
Number of Items	1
Number of items	1
Product benefits	Visibly refines the pores, improves the skin structure and ensures an even complexion, supports the regeneration of the skin and strengthens the skin barrier, increases radiance and provides a healthy glow, ideal for daily use for all skin types Product benefits Visibly refines the pores, improves the skin structure and ensures an even complexion, supports the regeneration of the skin and strengthens the skin barrier, increases radiance and provides a healthy glow, ideal for daily use for all skin types See more
Unit Count	30.0 millilitre

Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 30 ml

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